Article
Neisseria prophage repressor implicated in gonococcal pathogenesis.
Infection and immunity - 1 Oct 2013
Daou Nadine, Yu Chunxiao, McClure Ryan, Gudino Cynthia, Reed George W, Genco Caroline A
Abstract excerpt
Neisseria gonorrhoeae, the causative agent of the sexually transmitted disease gonorrhea, can infect and colonize multiple mucosal sites in both men and women. The ability to cope with different environmental conditions requires tight regulation of gene expression. In this study, we identified and characterized a gonococcal transcriptional regulatory protein (Neisseria phage repressor [Npr]) that was previously...
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