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Article

Tools for high efficiency genetic manipulation of the human pathogen Penicillium marneffei.

Fungal genetics and biology : FG & B - 1 Oct 2012

Bugeja Hayley E, Boyce Kylie J, Weerasinghe Harshini, Beard Sally, Jeziorowski Anne, Pasricha Shivani, Payne Michael, Schreider Lena, Andrianopoulos Alex

Abstract excerpt

Penicillium marneffei is an opportunistic pathogen of humans and displays a temperature dependent dimorphic transition. Like many fungi, exogenous DNA introduced by DNA mediated transformation is integrated randomly into the genome resulting in inefficient gene deletion and position-specific effects. To enhance successful gene targeting, the consequences of perturbing components of the non-homologous end joining...

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PMID: 22921264
DOI: 10.1016/j.fgb.2012.08.003

Genes

LIG4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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