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A role for the ATP-dependent DNA ligase Lig E of Neisseria gonorrhoeae in biofilm formation

2023-10-06

Abstract excerpt

The ATP-dependent DNA ligase Lig E is present as an accessory DNA ligase in numerous proteobacterial genomes, including many disease-causing species. Here we have constructed a genomic Lig E knock-out in the obligate human pathogen Neisseria gonorrhoeae and characterised its growth and infection characteristics. This demonstrates that N. gonorrhoeae Lig E is a non-essential gene and its deletion does not cause def...

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Identifiers and source

Literature Corpus work
14219459-2188-55b3-b4d0-3536eaae71d4
DOI
10.21203/rs.3.rs-3396984/v1
Open publication

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A role for the ATP-dependent DNA ligase Lig E of Neisseria gonorrhoeae in biofilm formationDOI 10.21203/rs.3.rs-3396984/v1
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