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Article

AP endonuclease paralogues with distinct activities in DNA repair and bacterial pathogenesis.

The EMBO journal - 7 Mar 2007

Carpenter Elisabeth P, Corbett Anne, Thomson Hellen, Adacha Jolanta, Jensen Kirsten, Bergeron Julien, Kasampalidis Ioannis, Exley Rachel, Winterbotham Megan, Tang Christoph, Baldwin Geoff S, Freemont Paul

Abstract excerpt

Oxidative stress is a principal cause of DNA damage, and mechanisms to repair this damage are among the most highly conserved of biological processes. Oxidative stress is also used by phagocytes to attack bacterial pathogens in defence of the host. We have identified and characterised two apurinic/apyrimidinic (AP) endonuclease paralogues in the human pathogen Neisseria meningitidis. The presence of multiple...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17318183
DOI: 10.1038/sj.emboj.7601593
PMCID: PMC1817638

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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