Article

Influence of the ATP-dependent DNA ligase, Lig E, on <i>Neisseria gonorrhoeae</i> microcolony and biofilm formation

2025-02-17

Abstract excerpt

<h4>Background</h4> Neisseria gonorrhoeae , the causative agent of the sexually transmitted infection, gonorrhoea, is known to form biofilms rich in extracellular DNA on human cervical cells. Biofilm formation is conducive to increased antimicrobial resistance and evasion of the host immune system, potentially causing asymptomatic infections. Using plate-based assays we have previously shown that disruption of a...

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Literature Corpus work: 63864ac2-e07b-552d-834b-7cb0d1741df6
DOI: 10.1101/2025.02.17.638724

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