Article

Mismatch Repair Deficiency in Colorectal Adenocarcinoma: Clinical, Pathological and Prognostic Features, a Single Center’s Experience of 1002 Cases

2021-07-28

Abstract excerpt

<h4>Background: </h4> and Study Aims: Microsatellite instability pathway caused by loss of DNA “Mismatch Repair genes” (MMR) is responsible of Lynch Syndrome-related tumors and 10-15% of sporadical colorectal cancers. Although MSI-test is regarded as the golden standard for detection of “Lynch Syndrome-related tumors”, there are increasing evidence on similar analytic sensitivity of immunohistochemical evaluations...

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Literature Corpus work: b9679b67-8db5-508e-a3dd-a2ca478ddc8c
DOI: 10.22541/au.162744808.83166972/v1

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