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Article

Molecular analysis of Iranian colorectal cancer patients at risk for Lynch syndrome: a new molecular, clinicopathological feature.

Journal of gastrointestinal cancer - 1 Jun 2015

Zeinalian Mehrdad, Emami Mohammad Hassan, Salehi Rasoul, Naimi Azar, Kazemi Mohammad, Hashemzadeh-Chaleshtori Morteza

Abstract excerpt

PURPOSE: Microsatellite instability (MSI) and mismatch repair (MMR) gene expression present a hallmark mutational signature of Lynch syndrome as a common hereditary cancer predisposing condition. Since there is not enough data of molecular and clinicopathological aspects of the disease in Iranian populations, this article is a new description in Central Iran. METHODS: It is a descriptive analytical study in which...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25722176
DOI: 10.1007/s12029-015-9696-1

Genes

MSH6
MLH1
MSH2
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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