Article

Clinicopathological Analysis and Literature Review of Four Cases of Lynch-like Syndrome

2025-08-07

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Among CRC patients with mismatch repair protein deficiency or microsatellite instability (MSI), up to 50% of cases lack germline mutations in MMR genes, <italic>BRAF</italic>mutations, or <italic>MLH1 </italic>promoter methylation. Such cases are defined as Lynch-like syndrome (LLS). LLS is a heterogeneous group of diseases that may include both sporadic and her...

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Literature Corpus work: 37599ec3-5c30-50b6-a6d0-4fd0ad3f2291
DOI: 10.21203/rs.3.rs-7247415/v1

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