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Article

The Relationship Between DNA Mismatch Repair Status and Clinicopathologic Characteristics in Colon Cancer.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 12 Aug 2024

Doğan Mehmet, Kılıç Mehmet, Tatlı Doğan Hayriye

Abstract excerpt

DNA mismatch repair (MMR) proteins are essential for repairing genetic mutations that occur during DNA replication. Deficiency of MMR proteins results in a phenotype called microsatellite instability (MSI), which occurs in Lynch syndrome as well as sporadic colorectal cancers (CRC), and it is associated with several clinicopathological features. We aimed to investigate the association of the loss of MMR proteins...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Mismatch Repair Endonuclease PMS2

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Identifiers

PMID: 39344689
DOI: 10.5152/tjg.2024.23366
PMCID: PMC11391230

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