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Oncological characteristics, treatments and prognostic outcomes in MMR-deficient colorectal cancer

26 Aug 2024

Abstract excerpt

Colorectal cancer (CRC) ranks as the third most prevalent cancer globally. It's recognized that the molecular subtype of CRC, characterized by mismatch repair deficiency (dMMR) or microsatellite instability-high (MSI-H), plays a critical role in determining appropriate treatment strategies. This review examines the current molecular classifications, focusing on dMMR/MSI-H CRC and its subtypes: Lynch syndrome...

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PMID: 39183366
DOI: 10.1186/s40364-024-00640-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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