Article

A sequence-based global map of regulatory activity for deciphering human genetics

2021-07-30

Abstract excerpt

Sequence is at the basis of how the genome shapes chromatin organization, regulates gene expression, and impacts traits and diseases. Epigenomic profiling efforts have enabled large-scale identification of regulatory elements, yet we still lack a sequence-based map to systematically identify regulatory activities from any sequence, which is necessary for predicting the effects of any variant on these activities. W...

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Literature Corpus work: 45c14a53-1c35-5370-afae-4bd6f1df6fe3
DOI: 10.1101/2021.07.29.454384

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