Article

Transmembrane Serine Protease TMPRSS11B promotes an acidified tumor microenvironment and immune suppression in lung squamous cell carcinoma

2025-04-03

Abstract excerpt

<h4>Summary</h4> Lung cancer is the leading cause of cancer-related deaths worldwide. Existing therapeutic options have limited efficacy, particularly for lung squamous cell carcinoma (LUSC), underscoring the critical need for the identification of new therapeutic targets. We previously demonstrated that the Transmembrane Serine Protease TMPRSS11B promotes transformation of human bronchial epithelial cells and e...

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Literature Corpus work: b946903e-e652-5f85-8f48-31ee8304dc0b
DOI: 10.1101/2025.04.01.646727

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