Article

<i>Acidovorax temperans</i> polarizes T17 cells and skews neutrophil maturation to promote lung adenocarcinoma development

2022-12-20

Abstract excerpt

<h4>SUMMARY</h4> Dysbiosis, or changes within the microbiome, is a common feature of solid tumors, however whether this dysbiosis directly contributes to tumor development is largely unknown. We previously characterized the lung cancer microbiome and identified Acidovorax temperans as enriched in tumors. In this study, we instilled A. temperans in an animal model driven by mutant Kras and Tp53 alleles. This r...

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Literature Corpus work: e03278bf-22ed-51a9-9201-aee058d0b11c
DOI: 10.1101/2022.12.20.521215

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