Article

Identification of splicing defects caused by novel exonic mutations in <i>LEF1</i> in Sudanese B- chronic lymphocytic leukemia patients: computational approach

2022-07-19

Abstract excerpt

<h4>Background</h4> Lymphocyte enhancer factor-1 (LEF-1) is a member of the LEF-1/TCF family of transcription factors that are critically involved in canonical Wnt/β-catenin Signaling to regulate B Lymphocyte proliferation and survival. Alteration of LEF1 expression and function leads to leukemogenesis as well as other several neoplasms. <h4>Aims</h4> to identify mutations in exons two and three of the LEF1 among...

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Literature Corpus work: b9405670-edea-56d2-aa34-2cecfb680870
DOI: 10.1101/2022.07.18.22277759

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Identification of splicing defects caused by novel exonic mutations in <i>LEF1</i> in Sudanese B- chronic lymphocytic leukemia patients: computational approachDOI 10.1101/2022.07.18.22277759Read

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