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Article

High resolution imaging and interpretation of three-dimensional RPE sheet structure

2024-12-04

Abstract excerpt

The retinal pigment epithelium (RPE), a monolayer of pigmented cells, is critical for visual function through its interaction with the neural retina. In healthy eyes, RPE cells exhibit a uniform hexagonal arrangement, but under stress or disease, such as age-related macular degeneration (AMD), dysmorphic traits like cell enlargement and apparent multinucleation emerge. Multinucleation has been hypothesized to resu...

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Literature Corpus work
b92701fd-2ae1-567c-a2b9-2cda9ff4e2a5
DOI
10.1101/2024.12.04.626881
Open publication

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