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Hyperreflective foci, OCT progression indicators in age-related macular degeneration, include transdifferentiated retinal pigment epithelium

2021-04-29

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose</h4> By optical coherence tomography (OCT) imaging, hyperreflective foci (HRF) indicate progression risk for advanced age-related macular degeneration (AMD) and are in part attributable to ectopic retinal pigment epithelium (RPE). We hypothesized that ectopic RPE are molecularly distinct from in-layer cells and that their cross-retinal course follows Müller glia. <h4>Method</h4> In cl...

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Literature Corpus work
7f1b00b6-0af5-50a2-bc9f-cfc740463e91
DOI
10.1101/2021.04.26.21256056
Open publication

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Hyperreflective foci, OCT progression indicators in age-related macular degeneration, include transdifferentiated retinal pigment epitheliumDOI 10.1101/2021.04.26.21256056
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