Article

A quantitative 3D Subcellular Map of Human Retinal Pigment Epithelium Discovers Non-stochastic Cell State Transition in Establishment of Apical/Basal Polarity

2024-10-15

Abstract excerpt

<title>Abstract</title> <p>The retinal pigment epithelium (RPE) is a specialized cell monolayer that forms the barrier between the subretinal and the choroidal spaces. During development RPE cells polarize perpendicular to the monolayer plane such that organelles attain specific intracellular locations. This allows the RPE to differentially interact with overlying photoreceptors and underlying choriocapillaris. W...

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Literature Corpus work: 9c756535-9603-5209-b44f-cd093aa32de5
DOI: 10.21203/rs.3.rs-5187667/v1

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