Mouse retinal cell behaviour in space and time using light sheet fluorescence microscopy

Abstract excerpt

As the general population ages and the incidence of diabetes increases epidemically, more people are affected by eye diseases, such as retinopathies. It is therefore critical to improve imaging of eye disease mouse models. Here, we demonstrate that 1) rapid, quantitative 3D and 4D (time lapse) imaging of cellular and subcellular processes in the murine eye is feasible, with and without tissue clearing, using light...

Topics

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• Equipment Design
• Mice, Transgenic
• Prenatal Diagnosis
• Reproducibility of Results
• Retinal Neoplasms
• Retinoblastoma
• Sensitivity and Specificity
• Tomography, Optical Coherence

Identifiers and source

Literature Corpus work

83d2da5a-d05c-5afc-846d-6f6ffd50de04

DOI

10.1101/686626