Article

Modeling tumors as species-rich ecological communities

2024-04-26

Abstract excerpt

Many advanced cancers resist therapeutic intervention. This process is fundamentally related to intra-tumor heterogeneity: multiple cell populations, each with different mutational and phenotypic signatures, coexist within a tumor and its metastatic nodes. Like species in an ecosystem, many cancer cell populations are intertwined in a complex network of ecological interactions. Most mathematical models of tumor ec...

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Literature Corpus work: b8d8ec40-2ff4-5357-a2f2-83b8841bc0e8
DOI: 10.1101/2024.04.22.590504

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