Article
A multispecies framework for modeling adaptive immunity and immunotherapy in cancer
2022-02-10
Abstract excerpt
<h4>ABSTRACT</h4> Predator-prey theory is commonly used to approximately describe tumor growth in the presence of selective pressure from the adaptive immune system. These interactions are mediated by the tumor immunopeptidome (what the tumor “shows” the body) and the T-cell receptor (TCR) repertoire (how well the body “sees” cancer cells). Importantly, both tumor and T cell populations are dynamic and in competi...
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Identifiers and source
- Literature Corpus work
- e1d03590-12e7-579f-81e6-fcabcd340a0b
- DOI
- 10.1101/2022.02.10.479985