Article
Quantifying the impact of a periodic presence of antimicrobial on resistance evolution in a homogeneous microbial population of fixed size
2018-03-08
Abstract excerpt
The evolution of antimicrobial resistance often occurs in a variable environment, as antimicrobial is given periodically to a patient or added and removed from a medium. This environmental variability has a huge impact on the microorganisms’ fitness landscape, and thus on the evolution of resistance. Indeed, mutations conferring resistance often carry a fitness cost in the absence of antimicrobial, which may be co...
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Identifiers and source
- Literature Corpus work
- b8ae0159-a1cc-582e-b091-ef5f1f8d8740
- DOI
- 10.1101/279091