Article

Antibiotic Resistance Increases Evolvability and Maximizes Opportunities Across Fitness Landscapes

2019-08-29

Abstract excerpt

Antibiotic resistance continues to grow as a public health problem. One of the reasons for this continued growth is that resistance to antibiotics is strongly selected for in the presence of antibiotics and weakly selected against after their removal. This is frequently thought to be due to the effects of compensatory mutations. However, compensatory mutations are often not found in clinically relevant strains of...

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Literature Corpus work: 40bba78c-f3e1-51e3-94f6-6bc8d97aa423
DOI: 10.1101/750729

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