Article

Computational prediction of MHC anchor locations guide neoantigen identification and prioritization

2020-12-08

Abstract excerpt

Neoantigens are novel peptide sequences resulting from sources such as somatic mutations in tumors. Upon loading onto major histocompatibility complex (MHC) molecules, they can trigger recognition by T cells. Accurate neoantigen identification is thus critical for both designing cancer vaccines and predicting response to immunotherapies. Neoantigen identification and prioritization relies on correctly predicting w...

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Literature Corpus work: b8aa686c-ff72-596c-a7cb-9a20ab8a01c6
DOI: 10.1101/2020.12.08.416271

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