Computational methods and data resources for predicting tumor neoantigens

Abstract excerpt

Neoantigens are tumor-specific antigens presented exclusively by cancer cells. These antigens are recognized as nonself by the host immune system, thereby eliciting an antitumor T-cell response. This response is significantly enhanced through neoantigen-based immunotherapies, such as personalized cancer vaccines. The repertoire of neoantigens is unique to each cancer patient, necessitating neoantigen prediction...

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