Article
Inflammation and Immune Response in Arrhythmogenic Cardiomyopathy: State-of-the-Art Review.
Circulation - 16 Nov 2021
Asatryan Babken, Asimaki Angeliki, Landstrom Andrew P, Khanji Mohammed Y, Odening Katja E, Cooper Leslie T, Marchlinski Francis E, Gelzer Anna R, Semsarian Christopher, Reichlin Tobias, Owens Anjali T, Chahal C Anwar A
Abstract excerpt
Arrhythmogenic cardiomyopathy (ACM) is a primary disease of the myocardium, predominantly caused by genetic defects in proteins of the cardiac intercalated disc, particularly, desmosomes. Transmission is mostly autosomal dominant with incomplete penetrance. ACM also has wide phenotype variability, ranging from premature ventricular contractions to sudden cardiac death and heart failure. Among other drivers and...
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