Article

Role of ANXA2, HSP90AA1 and PTK2B in synaptic homeostasis through microglial cells in the human entorhinal cortex in Alzheimer’s disease

2023-03-10

Abstract excerpt

<h4>Background: </h4> Alzheimer´s disease (AD), the most prevalent neurodegenerative disorder worldwide, is clinically characterized by cognitive deficits. Neuropathologically, AD brains accumulate deposits of amyloid-β (Aβ) and tau proteins. Furthermore, these misfolded proteins can propagate cell to cell in a prion-like manner and induce native proteins to become pathological. The entorhinal cortex (EC) is the e...

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Literature Corpus work: b8967542-7040-5dfa-bb34-e8f25bfac535
DOI: 10.21203/rs.3.rs-2651138/v1

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