Article

Interactions Between Dietary Metabolites and Regulatory Risk Variants for Human Colon Cancer

2025-09-08

Abstract excerpt

<h4>ABSTRACT</h4> Interactions between genetic variants and environmental factors influence malignancy risk, including for colorectal cancer (CRC). Prevalent CRC susceptibility loci reside predominantly in noncoding regulatory DNA where they may interact with dietary influences to dysregulate expression of specific genes predisposing to neoplasia. The impacts of CRC protective and risk dietary metabolites, butyra...

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Literature Corpus work: b190aa6d-33f3-59cb-97f3-afcf2533aad9
DOI: 10.1101/2025.09.05.674475

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