Article

Circadian regulation of Homologous Recombination by Cryptochrome1-mediated dampening of DNA end resection

2023-01-22

Abstract excerpt

Genomic stability maintenance requires the repair of DNA breaks in the most accurate fashion. So, an exquisite regulatory network controls the choice between different repair mechanisms to maximize genome integrity. This relies mostly at the level of DNA end resection, the initial steps of the homologous recombination. On the other hand, numerous cellular activities follow a 24 h oscillation known as the circadian...

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Literature Corpus work: b868a30e-efc8-5f27-b356-bf049f317244
DOI: 10.1101/2023.01.22.524239

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