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DNA Damage Clustering after Ionizing Radiation and Consequences in the Processing of Chromatin Breaks

24 Feb 2022

Abstract excerpt

Charged-particle radiotherapy (CPRT) utilizing low and high linear energy transfer (low-/high-LET) ionizing radiation (IR) is a promising cancer treatment modality having unique physical energy deposition properties. CPRT enables focused delivery of a desired dose to the tumor, thus achieving a better tumor control and reduced normal tissue toxicity. It increases the overall radiation tolerance and the chances of...

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PMID: 35268641
DOI: 10.3390/molecules27051540

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