Article

Lupus pathogenesis and autoimmunity are exacerbated by high fat diet–induced obesity in MRL/lpr mice

2022-08-22

Abstract excerpt

<title>Abstract</title> <p><italic>Background</italic>: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by persistent inflammation and autoantibody production, leading to systemic damage. Genetic predisposition and environmental factors such as high fat diet (HFD)/obesity may contribute to lupus development. In this study, we investigated the impact of HFD in lupus pathogenesis and autoi...

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Literature Corpus work: b851dcf4-490f-5e00-900a-991b447a1277
DOI: 10.21203/rs.3.rs-1969059/v1

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