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Article

Autosomal loci associated with a sex-related difference in the development of autoimmune phenotypes in a lupus model.

European journal of immunology - 1 Oct 2007

Misu Naoko, Zhang Mingcai, Mori Shiro, Miyazaki Tatsuhiko, Furukawa Hiroshi, Sasaki Takeshi, Nose Masato, Ono Masao

Abstract excerpt

Sex-related differences (SrD) are a general characteristic of human autoimmune diseases. There is an increasing body of evidence that suggests a link between sex-related hormones and autoimmune onsets. Here, through a genetic approach using a lupus mouse model, we attempted to show the involvement of genetic factors in the development of SrD in autoimmune diseases. Using MRL/lpr x (MRL/lpr x C57BL/6.Fas(lpr))F1...

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PMID: 17823981
DOI: 10.1002/eji.200637016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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