Article
Modulation of lupus phenotype by adiponectin deficiency in autoimmune mouse models.
Journal of clinical immunology - 1 Apr 2011
Parker Jennifer, Menn-Josephy Hanni, Laskow Bari, Takemura Yukihiro, Aprahamian Tamar
Abstract excerpt
Adiponectin is an adipocyte-derived cytokine with anti-inflammatory properties. Paradoxically, circulating adiponectin levels are increased in a number of inflammatory diseases. Thus, we sought to define the role of adiponectin deficiency in mouse models of autoimmunity. Adiponectin-deficient mic...
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