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Article

Development of pristane induced mice model for lupus with atherosclerosis and analysis of TLR expression.

Clinical and experimental rheumatology - 1 Jan 2000

Chen Xiaoqing, Cui RanRan, Li Rongda, Lin Huili, Huang Ziyang, Lin Ling

Abstract excerpt

OBJECTIVES: This study was designed to establish a murine model of lupus with atherosclerosis, and to investigate the expression of Toll-like receptors (TLRs) in the aorta and kidney. METHODS: The 9-week-old female ApoE-/- and C57BL/6 mice were randomly divided into a ApoE-/- pristane treated group (group A), ApoE-/- control group (group B), C57BL/6 pristane treated group (group C) and C57BL/6 control group...

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Source

Identifiers

PMID: 27385322

Genes

TLR2
TLR4
TLR7
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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