Article
Pathology of systemic lupus erythematosus: the challenges ahead.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014
Azevedo Pedro Correia, Murphy Grainne, Isenberg David A
Abstract excerpt
Many studies have explored the pathology of systemic lupus erythematosus (SLE), an autoimmune rheumatic disorder with a striking female predominance. Numerous autoimmune phenomena are present in this disease, which ultimately result in organ damage. However, the specific cellular and humoral mechanisms underlying the immune dysfunction are not yet fully understood. It is postulated that autoimmunity is based on...
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