Article

Parental genomes segregate into different blastomeres during multipolar zygotic divisions leading to mixoploid and chimeric blastocysts

2021-11-05

Abstract excerpt

The zygotic division enables two haploid genomes to segregate into two biparental diploid blastomeres. This fundamental tenet was challenged by the observation that blastomeres with different genome ploidy or parental genotypes can coexist within individual embryos. We hypothesized that whole parental genomes can segregate into distinct blastomere lineages during the first division through “heterogoneic division”....

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Literature Corpus work: b8499cb1-2f2f-56b4-a655-6e5ec888064c
DOI: 10.1101/2021.11.05.467317

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