Article
Overview of the killer cell immunoglobulin-like receptor system.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012
Rajalingam Raja
Abstract excerpt
Natural killer (NK) cells are more than simple killers and have been implicated in control and clearance of malignant and virally infected cells, regulation of adaptive immune responses, rejection of bone marrow transplants, and autoimmunity and the maintenance of pregnancy. Human NK cells largely use a family of germ-line encoded killer cell immunoglobulin-like receptors (KIR) to respond to the perturbations...
Topics
- HLA Antigens
- Humans
- Killer Cells, Natural
- Phenotype
- Receptors, KIR