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Article

MHC class I-specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response.

Blood - 15 Sept 2008

Yawata Makoto, Yawata Nobuyo, Draghi Monia, Partheniou Fotini, Little Ann-Margaret, Parham Peter

Abstract excerpt

Variegated expression of 6 inhibitory HLA class I-specific receptors on primary NK cells was studied using high-dimension flow cytometry in 58 humans to understand the structure and function of NK-cell repertoires. Sixty-four subsets expressing all possible receptor com-binations were present in each repertoire, and the frequency of receptor-null cells varied among the donors. Enhancement in missing-self response...

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Share to Histocompatibility Antigens Class I
Share to Killer Cells, Natural

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to NK Cell Lectin-Like Receptor Subfamily C

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Source

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Identifiers

PMID: 18583565
DOI: 10.1182/blood-2008-03-143727
PMCID: PMC2532809

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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