Article
Receptor-ligand analyses define minimal killer cell Ig-like receptor (KIR) in humans.
Immunogenetics - 1 Jan 2007
Du Zeying, Gjertson David W, Reed Elaine F, Rajalingam Raja
Abstract excerpt
Interactions between inhibitory killer cell immunoglobulin-like receptors (iKIR) and human leukocyte antigen (HLA) class I molecules regulate natural killer (NK) cell responses to eliminate infected and transformed cells while maintaining tolerance to healthy cells. Unlinked polymorphic gene families encode KIR receptors and HLA class I ligands and their independent segregation results in a variable number and...
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