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Computational Assessment of Phytochemical Inhibitors of Cytochrome P450 2E1 (CYP2E1) Implicated in Hepatotoxicity: Comparative Molecular Docking and Interaction Analysis Using Silymarin as a Benchmark

2026-06-02

Abstract excerpt

<title>Abstract</title> <p>Liver diseases remain a major global health challenge, often driven by oxidative stress and reactive metabolites generated during xenobiotic metabolism. Cytochrome P450 2E1 (CYP2E1) plays a central role in hepatotoxicity through the bioactivation of toxic compounds and excessive production of reactive oxygen species. This study aimed to evaluate the inhibitory potential of selected phyt...

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Literature Corpus work: b7f5185c-bba1-5d78-bfc9-2d56209a68e0
DOI: 10.21203/rs.3.rs-9862849/v1

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Computational Assessment of Phytochemical Inhibitors of Cytochrome P450 2E1 (CYP2E1) Implicated in Hepatotoxicity: Comparative Molecular Docking and Interaction Analysis Using Silymarin as a BenchmarkDOI 10.21203/rs.3.rs-9862849/v1Read

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