Article

In Silico Drug Discovery: Unveiling Potential Targets in Plasmodium falciparum through Molecular Docking Analysis

2024-02-26

Abstract excerpt

<title>Abstract</title> <p>The most significant human health problem is malaria, caused by the Plasmodium parasite and affecting nearly half of the global population. Malaria results in an annual death toll ranging from 1.2 to 2.7 million worldwide. Consequently, there is a pressing need for novel active ingredients with targeted effects to curb the worldwide spread of malaria. The objective of the present resear...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 27214f43-a63e-5b04-b7a3-52d0fb56b837
DOI: 10.21203/rs.3.rs-3981337/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

In Silico Drug Discovery: Unveiling Potential Targets in Plasmodium falciparum through Molecular Docking AnalysisDOI 10.21203/rs.3.rs-3981337/v1Read

In silico drug discovery: Unveiling potential targets in Plasmodium falciparumSemantic proximity Read

Two Coumarin Compounds Isolated from Scadoxus Multiflorus as a Potential Therapeutic Candidates against Plasmodium Falciparum Enzymes through Insilco ApproachSemantic proximity Read

Computational Analysis of Luteolin, Apigenin and Their Derivatives from Allophylus africanus as Potential Inhibitors of Plasmepsin II a Malaria TargetSemantic proximity Read

Target-similarity search using Plasmodium falciparum proteome identifies approved drugs with anti-malarial activity and their possible targetsSemantic proximity Read

Orthosteric-allosteric dual inhibitors of PfHT1 as selective anti-malarial agentsSemantic proximity Read

Identification of novel Plasmodium falciparum dihydroorotate dehydrogenase inhibitors for malaria using in silico studiesSemantic proximity Read

Computational studies of drug repurposing targeting P-glycoprotein mediated multidrug-resistance phenotypes in agents of neglected tropical diseasesSemantic proximity Read

Computer-aided drug design approaches applied to screen natural product’s structural analogs targeting arginase in Leishmania sppSemantic proximity Read

Protein target similarity is positive predictor of in vitro antipathogenic activity: a drug repurposing strategy for Plasmodium falciparumSemantic proximity Read

Novel antimalarial drug targets: hope for new antimalarial drugsSemantic proximity Read

In Silico Development and Assessment of Hybrid Antimalarials as Falcipain InhibitorsSemantic proximity Read

Whole-genome and mitogenome based in silico analysis of select <i>Plasmodium</i> and identification of a novel drug molecule against the malaria parasiteSemantic proximity Read