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Article

<i>In-Silico</i> Analysis of Secondary Metabolites that Modulates Enzymes of Cholesterol Target

2020-07-25

Abstract excerpt

Hypercholesterolemia has posed a serious threat of heart diseases and stroke worldwide. Xanthine oxidase (XO), the rate-limiting enzyme in uric acid biosynthesis, is regarded as the root of reactive oxygen species (ROS) that generates atherosclerosis and cholesterol crystals. β-Hydroxy β-methylglutaryl-coenzyme A reductase (HMGR) is a rate-limiting enzyme in cholesterol biosynthesis. Although some commercially ava...

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Literature Corpus work
4f5bc652-9a0c-56b6-b490-3ecb69d2a162
DOI
10.1101/2020.07.24.219998
Open publication

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