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In Silico exploration for potent phytochemicals targeting Helicobacter pylori: assessment of ADMET profiles and molecular docking analysis

2024-10-02

Abstract excerpt

Treatment of Helicobacter pylori (H. pylori) infections faces challenges such as drug adherence, drug resistance, and re-infection. Surface antigens like BabA and SabA cause the disease, while phytochemicals like glycyrrhizin and cinnamaldehyde in liquorice and cinnamon are highly absorbed by H. pylori. Other molecules like coumarin can disrupt H. pylori adherence. Optimizing pharmacokinetics of certain drugs rema...

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Literature Corpus work
fdf2d00a-c20e-5aac-a14f-762ef75a8424
DOI
10.1007/s44371-024-00028-4
Open publication

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In Silico exploration for potent phytochemicals targeting Helicobacter pylori: assessment of ADMET profiles and molecular docking analysisDOI 10.1007/s44371-024-00028-4
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