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Assessment of the CYP1A2 Inhibition-Mediated Drug Interaction Potential for Pinocembrin Using In Silico , In Vitro , and In Vivo Approaches

2 Jun 2022

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide Pinocembrin, a bioflavonoid, is extensively used in complementary/alternative medicine. It turns out as a promising candidate against neurodegenerative diseases because of its multifaceted pharmacological action toward neuroprotection. However, literature evidence is still lacking for its inhibitory action on CYP1A2, which is responsible for xenobiotic metabolism...

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PMID: 35721953
DOI: 10.1021/acsomega.2c02315

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