Back to search

Article

An in vivo and in silico evaluation of the magical hepatoprotective potentialities of Gynura procumbens: a promising agent for combating hepatotoxicity

2022-05-11

Abstract excerpt

<h4>Introduction</h4> Liver being the most important metabolic organ of the body performs a wide variety of vital functions. Hepatic cell injury occurs by the activation of reactive oxygen species (ROS) by CCl 4 , xenobiotics and other toxic substances generated through cytochrome P450 dependent step resulting from covalent bond formation with lipoproteins and nucleic acids. Observing the alarming state of hepat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8ea6d9e0-dbd4-5bf6-8f55-61b0e9b05075
DOI
10.1101/2022.05.11.491443
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
An in vivo and in silico evaluation of the magical hepatoprotective potentialities of Gynura procumbens: a promising agent for combating hepatotoxicityDOI 10.1101/2022.05.11.491443
Phytochemical Screening, Investigation of the toxic and hepatoprotective effect of leaves of <i>Prunus africana</i> -using mice modelSemantic proximity
Advanced Strategies in Enhancing the Hepatoprotective Efficacy of Natural Products: Integrating Nanotechnology, Genomics, and Mechanistic InsightsSemantic proximity
Hepatoprotective Role of Emodin in Chemical-Induced Liver Injury histopathological study in Mice ModelSemantic proximity
Oxidative Stress Modulation and Organ Protection by Mondia whitei: Phytochemistry, Mechanisms, and Therapeutic PotentialSemantic proximity
A review on potential antioxidant effects of Cumin (Cuminum cyminum), phytochemical Profile and its usesSemantic proximity
ANTIOXIDANT AND TOXICOLOGICAL EVALUATION OF VIGNA SUBTERRANEAN SEED BAMBARA NUT FRACTIONS ON HIGH FAT DIETS INDUCED OXIDATIVE STRESS MALE WISTAR RATSSemantic proximity
Antioxidant analysis, induced toxicology, spectroscopy and HPLC, GC–MS characterization of Argyrolobium arabicum (Decne.) Jaub. & SpachSemantic proximity
The potential mechanism and chemical compounds contributed to Psoraleae Fructus-induced hepatotoxicity from the aspect of mitochondrial dysfunctionSemantic proximity
Pueraria Flos Alleviates Alcoholic Liver Injury Via Regulation of PPARα and MAOA: Deciphering the Effective Forms and Potential Mechanism Based on a Bioinformatics-Integrated Metabolic Profile Strategy and Experimental ValidationSemantic proximity
Free Radical Scavenging Activity and Oxidative Stress Inhibition of Dalbergiella welwitschii Essential Oils: Evidence from Experimental and Computational StudiesSemantic proximity
<i>In vitro</i> Anti-Cancer Activity of <i>Oliveria decumbens</i> Vent. Extract, an Endemic Persian Medicinal Plant, on HT-29 Colorectal Cancer Cell LineSemantic proximity
Integrated in silico dissection of ABC transporter- mediated hepatoprotective by apigenin and luteolin from Eclipta prostrata using network pharmacology, molecular docking and ADME-toxicity profilingSemantic proximity
Select a neighboring publication to make it the new centre.