Article

Computer-aided drug design approaches applied to screen natural product’s structural analogs targeting arginase in Leishmania spp

2023-07-13

Abstract excerpt

<h4>Introduction: </h4> Leishmaniasis is a disease with high mortality rates and approximately 1.5 million new cases each year. Despite the new approaches and advances to fight the disease, there are no effective therapies. <h4>Methods: </h4>: Hence, this study aims to screen for natural products' structural analogs as new drug candidates against leishmaniasis. We applied Computer-aided drug design (CADD) approac...

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Literature Corpus work: dee2888b-7715-5c1e-bfbc-ecde82b1e3ee
DOI: 10.12688/f1000research.129943.3

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