Article

Developmental deficits, synapse and dendritic abnormalities in a Clcn4 KO autism mice model : Endophenotypic target for ASD

2023-10-03

Abstract excerpt

<title>Abstract</title> Chloride voltage-gated channel-4 (Clcn4) deletion is associated with autism spectrum disorder (ASD) in humans. Previous studies reported that Clcn4 knockout (KO) mice do not exhibit neurological alterations in the brain. In the present study, Clcn 4 KO C57BL/6 mice was assessed using three chamber test and marble burying test at 7 to 8 weeks of age, KO mice showed reduction in social in...

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Literature Corpus work: b7e064c7-7a88-5a95-af9d-9e4463e5b667
DOI: 10.21203/rs.3.rs-3171079/v1

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