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Article

Mutations associated with autism lead to similar synaptic and behavioral alterations in both sexes of male and female mouse brain.

Scientific reports - 4 Jan 2024

Tripathi Manish Kumar, Ojha Shashank Kumar, Kartawy Maryam, Khaliulin Igor, Hamoudi Wajeha, Amal Haitham

Abstract excerpt

Autism spectrum disorder (ASD) is a neurodevelopmental disorder based on synaptic abnormalities. The estimated prevalence rate of male individuals diagnosed with ASD prevails over females is in a proportion of 4:1. Consequently, males remain the main focus in ASD studies in clinical and experimental settings. Meanwhile, some studies point to an underestimation of this disorder in females. In this work, we studied...

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Identifiers

PMID: 38177238
DOI: 10.1038/s41598-023-50248-4
PMCID: PMC10766975

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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