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<i>Cis</i> - and <i>trans</i> -eQTL TWAS of breast and ovarian cancer identify more than 100 risk associated genes in the BCAC and OCAC consortia

2023-11-13

Abstract excerpt

<h4>ABSTRACT</h4> Transcriptome-wide association studies (TWAS) have investigated the role of genetically regulated transcriptional activity in the etiologies of breast and ovarian cancer. However, methods performed to date have only considered regulatory effects of risk associated SNPs thought to act in cis on a nearby target gene. With growing evidence for distal ( trans ) regulatory effects of variants on ge...

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Literature Corpus work
04d33f77-ff8f-5fb3-b7e5-f92ae4af182e
DOI
10.1101/2023.11.09.566218
Open publication

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<i>Cis</i> - and <i>trans</i> -eQTL TWAS of breast and ovarian cancer identify more than 100 risk associated genes in the BCAC and OCAC consortiaDOI 10.1101/2023.11.09.566218
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