Article

Deep learning enables direct HLA typing from immunopeptidomics data

2026-04-10

Abstract excerpt

The immune system eliminates malignant and infected cells through T-cell-mediated recognition of peptides presented by human leukocyte antigen molecules. Mass spectrometry-based immunopeptidomics enables unbiased identification of naturally presented HLA-restricted peptides and has become central to the development of T-cell-based immunotherapies. However, immunopeptidomics data reflects the combined peptide prese...

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Literature Corpus work: b7a86860-e50a-5de4-ae3e-70cbb8f21e5b
DOI: 10.64898/2026.04.08.717021

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