Article

HLAIIPred: Cross-Attention Mechanism for Modeling the Interaction of HLA Class II Molecules with Peptides

2024-10-03

Abstract excerpt

We introduce HLAIIPred, a deep learning model to predict peptides presented by class II human leukocyte antigens (HLAII) on the surface of antigen presenting cells. HLAIIPred is trained using a Transformer-based neural network and a dataset comprising of HLAII-presented peptides identified by mass spectrometry. In addition to predicting peptide presentation, the model can also provide important insights into pepti...

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Literature Corpus work: ea15a910-afa1-5e4b-8be8-be71f0aa86f4
DOI: 10.1101/2024.10.01.616078

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